Cuure personalizes through an online questionnaire. Singular personalizes through blood analysis, with a longevity focus targeting the hallmarks of cellular aging. These are two fundamentally different approaches to supplementation. Cuure selects 2 to 8 capsules from an existing catalog based on your self-reported answers. Singular formulates a single powder, dosed to the milligram, based on 28+ actual blood biomarkers.
| Criterion | Singular | Cuure |
|---|---|---|
| Personalization | Blood + questionnaire Analysis of your actual blood biomarkers | Online quiz (40–70 questions) Self-reported personalization without biological measurement |
| Product format | Single powder (mg-level dosing) One integrated formula, not separate capsules | Sachets of separate capsules (2–8/day) Products selected from an existing catalog |
| Biomarkers analyzed | 31 biomarkers Longevity-oriented comprehensive panel analyzed by the algorithm | 0 No biological analysis |
| Possible bioactives | 32 bioactives Selected to target the biological hallmarks of aging | 2–8 selected products Chosen from a catalog of 100+ references |
| Price / month | €299/month Results analysis + formula + delivery included | ~35 €/month Monthly subscription with no commitment |
| Commitment | No commitment Cancel anytime, no questions asked | No commitment Free cancellation anytime |
| Manufacturing | France (in-house laboratory) Fully vertically integrated | France Outsourced production through subcontractors |
| Quality and security | Food safety plan · HDS hosting GHP and HACCP principles; providers' certified scopes | Variable Depends on the suppliers used |
| Scientific validation | Independent scientific committee Experts in longevity medicine, pharmacology, cellular biology, nutrition | Scientific advisory board General nutrition focus, no longevity specialization |
| Delivery | FR, EU, UK, CH, US Free delivery included | EU + UK Home delivery in Europe |
The Cuure quiz asks 40 to 70 questions about your lifestyle, symptoms, and goals. It's a relevant orientation tool, but it relies entirely on self-reported data. Fatigue can have dozens of different causes, which only a blood test can differentiate.
A person can feel fine and still have a shortfall in vitamin D, zinc, or vitamin B12. These silent shortfalls don't show up in any questionnaire. Conversely, a reported symptom may not correspond to any measurable shortfall.
Singular integrates a health questionnaire AND a blood test. The questionnaire provides context; the blood test provides measurements.
Cuure selects existing products from its catalog and assembles them in a monthly sachet. Each capsule was formulated independently for the mass market. Interactions between nutrients (synergies or antagonisms) are not optimized at the formula level.
Singular produces a single powder formula where each bioactive is dosed to the milligram according to its applicable rule: some keep a fixed base dose, while others may be adjusted from blood results. Cofactors are integrated from the design stage. Magnesium and vitamin B6 are combined in the same serving. Iron is separated from calcium.
This architectural difference (assembly of finished products vs individual formulation) defines the achievable level of precision.
Cuure charges approximately 35 € per month for a sachet of quiz-selected capsules. This price covers algorithmic selection, products, and delivery. It's an accessible price point.
Singular charges €299 per month. This price includes algorithmic analysis of 31 imported biomarkers, formulation, individual manufacturing of a precision powder in an in-house French laboratory under a Food Safety Plan based on GHP and HACCP principles, and delivery. The blood draw remains performed by the laboratory of your choice.
The two services don't address the same need. Cuure offers symptom-guided selection. Singular offers biology-driven individual calibration. The price gap reflects the method gap.
Cuure claims approximately 400,000 users. The quiz-based approach makes the service accessible to the widest audience. For a healthy person looking for basic supplementation, it's a coherent option.
Singular is for people who want measurable precision. The initial blood test provides a quantified baseline. Follow-up panels describe how measured markers evolve. Each formula is adjusted based on objective data. Bioactive selection is supervised by an independent scientific committee — experts in longevity medicine, pharmacology, and cellular biology. Every ingredient must satisfy three inclusion criteria: human benefit demonstrated through meta-analyses or randomized trials, documented bioavailability, and a favorable benefit-risk ratio. The scientific framework is built on the 14 hallmarks of cellular aging (López-Otín & Kroemer, Cell 2025) — a longevity orientation that quiz-based approaches, centered on self-reported symptoms, do not offer.
Quiz-based personalization and blood-based personalization are not two versions of the same service. They are two distinct product categories.