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Our bioactives library

Each bioactive is selected for its benefit demonstrated in humans and its documented bioavailability.

Every dosage shown states the pure active substance itself, excluding excipients and carriers. The raw material weighed in the laboratory is always heavier than the figure displayed.

Phytonutrients

Astaxanthin

Oxidative stress

Red carotenoid pigment extracted from Haematococcus pluvialis microalgae, one of the most concentrated natural sources of astaxanthin. This encapsulated form is water-dispersible: astaxanthin, fat-soluble in its natural state, is carried by a modified corn starch matrix that allows homogeneous dispersion in aqueous media. To date, no published human study compares the absorption of this form with that of the oils and oleoresins used in the trials. A blend of natural tocopherols protects the pigment from oxidation within this matrix. The guaranteed assay covers total free astaxanthin, the sum of its isomers. The all-trans isomer is predominant at batch control.

Astaxanthin belongs to the carotenoid family (plant pigments), which the human body does not make itself. In healthy adults, controlled trials measure a rise above placebo in the amount of ultraviolet light needed to redden the skin. That measurement is made under ultraviolet exposure conducted in a laboratory. That result, measured in humans, earns its place in the formula.

0 to 6 mg

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Astaxanthin
Phytonutrients

Astaxanthin

Oxidative stress

Red carotenoid pigment extracted from Haematococcus pluvialis microalgae, one of the most concentrated natural sources of astaxanthin. This encapsulated form is water-dispersible: astaxanthin, fat-soluble in its natural state, is carried by a modified corn starch matrix that allows homogeneous dispersion in aqueous media. To date, no published human study compares the absorption of this form with that of the oils and oleoresins used in the trials. A blend of natural tocopherols protects the pigment from oxidation within this matrix. The guaranteed assay covers total free astaxanthin, the sum of its isomers. The all-trans isomer is predominant at batch control.

Astaxanthin belongs to the carotenoid family (plant pigments), which the human body does not make itself. In healthy adults, controlled trials measure a rise above placebo in the amount of ultraviolet light needed to redden the skin. That measurement is made under ultraviolet exposure conducted in a laboratory. That result, measured in humans, earns its place in the formula.

0 to 6 mg

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Phytonutrients

Black Garlic

Vascular tonePatented active

Abg10+® (Garlace®) is an aqueous extract of aged black garlic bulbs (Allium sativum L.). The process combines controlled temperature and humidity, followed by water extraction. It is an ageing process involving the Maillard reaction, without microbial fermentation. The extract is standardised through an organosulfur compound profile that includes S-allyl-cysteine (SAC). It is also the material evaluated in the controlled trial conducted in adults with hypertension. The selected material uses maltodextrin as a carrier. It retains a characteristic aroma and taste, with less pungency than fresh garlic.

Black garlic comes from the same bulb as the garlic used in cooking, after ageing. That ageing removes the pungent compound of raw garlic. In adults being followed for raised blood pressure, a controlled trial records a favourable change in readings taken at home. That result, measured on the aged bulb itself, earns its place in the formula.

0 to 1,200 mg

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Black Garlic
Phytonutrients

Black Garlic

Vascular tonePatented active

Abg10+® (Garlace®) is an aqueous extract of aged black garlic bulbs (Allium sativum L.). The process combines controlled temperature and humidity, followed by water extraction. It is an ageing process involving the Maillard reaction, without microbial fermentation. The extract is standardised through an organosulfur compound profile that includes S-allyl-cysteine (SAC). It is also the material evaluated in the controlled trial conducted in adults with hypertension. The selected material uses maltodextrin as a carrier. It retains a characteristic aroma and taste, with less pungency than fresh garlic.

Black garlic comes from the same bulb as the garlic used in cooking, after ageing. That ageing removes the pungent compound of raw garlic. In adults being followed for raised blood pressure, a controlled trial records a favourable change in readings taken at home. That result, measured on the aged bulb itself, earns its place in the formula.

0 to 1,200 mg

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Phytonutrients

Cocoa Flavanols

Vascular tonePatented active

CocoActiv® is a cocoa bean (Theobroma cacao) extract standardised to at least 30% cocoa flavanols. Among these native polyphenols, epicatechin is the most studied. The extraction process preserves the flavanol fraction that industrial cocoa processing, particularly roasting and alkalisation, largely degrades. This specification provides consistent content from batch to batch. Powder with no excipient.

Cocoa flavanols are plant compounds the body does not make, and that reach it through food. In healthy adults, a controlled trial measures arteries that dilate more as blood passes through them and stiffen less. Further trials in women find skin that reddens less after controlled ultraviolet exposure, and fainter wrinkles. These results, obtained in humans on vessels and skin alike, are what earn them a place in the formula.

0 to 350 mg

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Cocoa Flavanols
Phytonutrients

Cocoa Flavanols

Vascular tonePatented active

CocoActiv® is a cocoa bean (Theobroma cacao) extract standardised to at least 30% cocoa flavanols. Among these native polyphenols, epicatechin is the most studied. The extraction process preserves the flavanol fraction that industrial cocoa processing, particularly roasting and alkalisation, largely degrades. This specification provides consistent content from batch to batch. Powder with no excipient.

Cocoa flavanols are plant compounds the body does not make, and that reach it through food. In healthy adults, a controlled trial measures arteries that dilate more as blood passes through them and stiffen less. Further trials in women find skin that reddens less after controlled ultraviolet exposure, and fainter wrinkles. These results, obtained in humans on vessels and skin alike, are what earn them a place in the formula.

0 to 350 mg

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Peptides

Collagen Type II

Tissue structurePatented active

Nuvicol® II provides at least 3% non-denatured type II collagen, with no added excipient. The non-denatured form preserves collagen's native three-dimensional structure and specific epitopes, unlike a hydrolysed form. Its cartilage matrix also contains chondroitin sulphate and hydroxyproline, structural components of hyaline cartilage. Type II collagen is the predominant protein in articular cartilage. Manufactured in the Netherlands.

Type II collagen is the protein that gives cartilage its strength. In adults whose knee shows wear, a controlled trial measures better knee comfort and function scores than on placebo. Another trial measures, in healthy adults whose knee troubles them during exercise, a joint that bends further than on placebo. Collagen types I and III, also present in the formula, plays a different role: it supplies amino acids. These results, measured in humans, are what earn type II its place in the formula.

0 to 40 mg

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Collagen Type II
Peptides

Collagen Type II

Tissue structurePatented active

Nuvicol® II provides at least 3% non-denatured type II collagen, with no added excipient. The non-denatured form preserves collagen's native three-dimensional structure and specific epitopes, unlike a hydrolysed form. Its cartilage matrix also contains chondroitin sulphate and hydroxyproline, structural components of hyaline cartilage. Type II collagen is the predominant protein in articular cartilage. Manufactured in the Netherlands.

Type II collagen is the protein that gives cartilage its strength. In adults whose knee shows wear, a controlled trial measures better knee comfort and function scores than on placebo. Another trial measures, in healthy adults whose knee troubles them during exercise, a joint that bends further than on placebo. Collagen types I and III, also present in the formula, plays a different role: it supplies amino acids. These results, measured in humans, are what earn type II its place in the formula.

0 to 40 mg

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Peptides

Collagen Types I and III

Tissue structure

Peptan® B 2000 LD provides additive-free hydrolysed collagen peptides of types I and III with an average molecular weight of 2,000 daltons and instant solubility. Hydrolysis breaks the chains into short peptides, found in human blood as di- and tripeptides after intake. The ingredient provides collagen-specific amino acids, particularly glycine, proline and hydroxyproline, which are scarce in other dietary protein sources. Manufactured in France at Rousselot's Angoulême site.

Type I collagen is the most abundant protein in the body; type III sits alongside it in skin and tendons. In adults, pooled controlled trials measure more hydrated, more supple skin and shallower wrinkles after oral supplementation. In women past the menopause with reduced bone density, a controlled trial records a rise in that density at the spine and the femoral neck. These results, measured in humans, are what earn type I and III collagen a place in the formula.

0 to 5 g

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Collagen Types I and III
Peptides

Collagen Types I and III

Tissue structure

Peptan® B 2000 LD provides additive-free hydrolysed collagen peptides of types I and III with an average molecular weight of 2,000 daltons and instant solubility. Hydrolysis breaks the chains into short peptides, found in human blood as di- and tripeptides after intake. The ingredient provides collagen-specific amino acids, particularly glycine, proline and hydroxyproline, which are scarce in other dietary protein sources. Manufactured in France at Rousselot's Angoulême site.

Type I collagen is the most abundant protein in the body; type III sits alongside it in skin and tendons. In adults, pooled controlled trials measure more hydrated, more supple skin and shallower wrinkles after oral supplementation. In women past the menopause with reduced bone density, a controlled trial records a rise in that density at the spine and the femoral neck. These results, measured in humans, are what earn type I and III collagen a place in the formula.

0 to 5 g

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Amino acids

Creatine

Mitochondrial energy

Micronised creatine monohydrate (200 mesh). Micronisation reduces particle size to an ultrafine level, which favours dispersibility in solution and dissolution speed at the time of preparation. The monohydrate form is the most scientifically documented among all available creatine forms. Creatine is a molecule naturally synthesised by the body from arginine, glycine and methionine, stored primarily in skeletal muscle. Pure raw material. No excipient.

Often associated with weight training, creatine is a molecule that muscle, heart and brain use to renew their energy quickly. Creatine increases physical performance in successive bursts of short-term, high intensity exercise (the beneficial effect is obtained with a daily intake of 3 g of creatine). Measurements taken in muscle show a store that fills gradually, which makes regular intake the condition of the effect. That maintained store is what earns creatine its place in the formula.

0 to 3 g

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Creatine
Amino acids

Creatine

Mitochondrial energy

Micronised creatine monohydrate (200 mesh). Micronisation reduces particle size to an ultrafine level, which favours dispersibility in solution and dissolution speed at the time of preparation. The monohydrate form is the most scientifically documented among all available creatine forms. Creatine is a molecule naturally synthesised by the body from arginine, glycine and methionine, stored primarily in skeletal muscle. Pure raw material. No excipient.

Often associated with weight training, creatine is a molecule that muscle, heart and brain use to renew their energy quickly. Creatine increases physical performance in successive bursts of short-term, high intensity exercise (the beneficial effect is obtained with a daily intake of 3 g of creatine). Measurements taken in muscle show a store that fills gradually, which makes regular intake the condition of the effect. That maintained store is what earns creatine its place in the formula.

0 to 3 g

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Phytonutrients

Curcumin

Systemic inflammationPatented active

Meriva™ is a patented complex of turmeric-derived curcuminoids and sunflower-lecithin phospholipids, standardised to 18-22% total curcuminoids. These polyphenols give the turmeric rhizome (Curcuma longa) its characteristic orange colour. Extraction with food-grade ethyl acetate yields a native extract at a 30:1 ratio. The resulting complex is carried on microcrystalline cellulose (E460(i)). Turmeric has been used in Ayurvedic tradition for millennia. As curcumin is naturally fat-soluble and poorly absorbed on its own, the phospholipid carrier is an integral part of the ingredient. Preservative-free.

Curcumin is a plant compound from turmeric, a spice used in Indian cooking. In adults, pooled controlled trials measure, in the blood, a drop in an inflammation marker and a rise in the defences against oxidative wear. Other trials, run in adults with worn knee cartilage, record less pain and easier everyday movement. Those measurements, obtained in humans, are what earn it a place in the formula.

0 to 125 mg

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Curcumin
Phytonutrients

Curcumin

Systemic inflammationPatented active

Meriva™ is a patented complex of turmeric-derived curcuminoids and sunflower-lecithin phospholipids, standardised to 18-22% total curcuminoids. These polyphenols give the turmeric rhizome (Curcuma longa) its characteristic orange colour. Extraction with food-grade ethyl acetate yields a native extract at a 30:1 ratio. The resulting complex is carried on microcrystalline cellulose (E460(i)). Turmeric has been used in Ayurvedic tradition for millennia. As curcumin is naturally fat-soluble and poorly absorbed on its own, the phospholipid carrier is an integral part of the ingredient. Preservative-free.

Curcumin is a plant compound from turmeric, a spice used in Indian cooking. In adults, pooled controlled trials measure, in the blood, a drop in an inflammation marker and a rise in the defences against oxidative wear. Other trials, run in adults with worn knee cartilage, record less pain and easier everyday movement. Those measurements, obtained in humans, are what earn it a place in the formula.

0 to 125 mg

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Microbiota

Galacto-oligosaccharides (GOS)

Microbiome & barrierPatented active

Vivinal® GOS is a concentrated soluble galacto-oligosaccharide fibre produced using proprietary enzymatic technology. These non-digestible prebiotics serve as a selective substrate for beneficial gut bacteria, particularly bifidobacteria. The ingredient contains a spectrum of oligosaccharide chains from DP2 to DP8, or 2 to 8 galactose units. Its taste is slightly sweet. This powder consists of 97% milk solids: 69% GOS, 23% lactose and other disaccharides, and 5% glucose and galactose.

GOS are fibres made of short sugar chains that digestive enzymes cannot break down. They reach the large intestine whole, where bifidobacteria, a family of gut bacteria, feed on them. In healthy adults, controlled trials measure a rise in the number of those bacteria. That result is found from one trial to the next, and it earns them their place in the formula.

0 to 5 g

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Galacto-oligosaccharides (GOS)
Microbiota

Galacto-oligosaccharides (GOS)

Microbiome & barrierPatented active

Vivinal® GOS is a concentrated soluble galacto-oligosaccharide fibre produced using proprietary enzymatic technology. These non-digestible prebiotics serve as a selective substrate for beneficial gut bacteria, particularly bifidobacteria. The ingredient contains a spectrum of oligosaccharide chains from DP2 to DP8, or 2 to 8 galactose units. Its taste is slightly sweet. This powder consists of 97% milk solids: 69% GOS, 23% lactose and other disaccharides, and 5% glucose and galactose.

GOS are fibres made of short sugar chains that digestive enzymes cannot break down. They reach the large intestine whole, where bifidobacteria, a family of gut bacteria, feed on them. In healthy adults, controlled trials measure a rise in the number of those bacteria. That result is found from one trial to the next, and it earns them their place in the formula.

0 to 5 g

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Phytonutrients

Ginger

Systemic inflammation

Ginger rhizome extract (Zingiber officinale), standardised in gingerols, the primary bioactive compounds of the plant. Extraction is performed from the whole rhizome by a hydro-alcoholic process, using ethanol and water. A 15:1 ratio concentrates fifteen parts of dried rhizome into one part of extract. The extract is standardised to at least 10% gingerols by HPLC, twice the assay of standard 5% extracts. Ginger has been used for millennia in Ayurvedic and Chinese traditions.

Ginger is the underground stem of a tropical plant, eaten as a spice known for its pungent taste. In healthy adults, a controlled trial measures a stomach that empties faster. Pooled controlled trials report lower blood markers of inflammation in adults. These results, measured in humans, are what earn it a place in the formula.

0 to 150 mg

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Ginger
Phytonutrients

Ginger

Systemic inflammation

Ginger rhizome extract (Zingiber officinale), standardised in gingerols, the primary bioactive compounds of the plant. Extraction is performed from the whole rhizome by a hydro-alcoholic process, using ethanol and water. A 15:1 ratio concentrates fifteen parts of dried rhizome into one part of extract. The extract is standardised to at least 10% gingerols by HPLC, twice the assay of standard 5% extracts. Ginger has been used for millennia in Ayurvedic and Chinese traditions.

Ginger is the underground stem of a tropical plant, eaten as a spice known for its pungent taste. In healthy adults, a controlled trial measures a stomach that empties faster. Pooled controlled trials report lower blood markers of inflammation in adults. These results, measured in humans, are what earn it a place in the formula.

0 to 150 mg

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Glycans

Glucosamine

Tissue structurePatented active

Amino sugar naturally present in cartilage. Quality: no excipient.

Glucosamine is a sugar, one of the constituents of the long chains that hold water and give cartilage its ability to absorb shock. After ingestion it passes into the blood, then into the fluid that lubricates the joint, where it is found. In adults with worn knees, pooled controlled trials measure less discomfort and less stiffness. Those results, measured in humans, are what earn it a place in the formula.

0 to 1,118 mg

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Glucosamine
Glycans

Glucosamine

Tissue structurePatented active

Amino sugar naturally present in cartilage. Quality: no excipient.

Glucosamine is a sugar, one of the constituents of the long chains that hold water and give cartilage its ability to absorb shock. After ingestion it passes into the blood, then into the fluid that lubricates the joint, where it is found. In adults with worn knees, pooled controlled trials measure less discomfort and less stiffness. Those results, measured in humans, are what earn it a place in the formula.

0 to 1,118 mg

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Amino acids

Glycine

Autophagy & Senescence

Glycine is the smallest and simplest of the amino acids. It accounts for roughly one third of the amino acids in collagen and provides one of the three building blocks of glutathione, the antioxidant that cells manufacture themselves. Depending on your profile, it may be present in your formula in two forms, both counted in the displayed dose. Added as a dedicated bioactive, it comes as free-form L-glycine: the amino acid on its own, not bound to another compound. The material selected is European Pharmacopoeia grade, with an assay between 98.5 and 101.5%. Delivered through magnesium, it comes as magnesium bisglycinate, a salt in which two glycine molecules are bound to a magnesium atom.

Glycine is an amino acid, a basic building block of proteins. In adults dissatisfied with their sleep, the trials find faster sleep onset and nights rated as better. In the laboratory, glycine lowers body temperature in animals, a signal that accompanies falling asleep. That result, measured in humans, is what grounds its place in the formula.

0 to 3 g

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Glycine
Amino acids

Glycine

Autophagy & Senescence

Glycine is the smallest and simplest of the amino acids. It accounts for roughly one third of the amino acids in collagen and provides one of the three building blocks of glutathione, the antioxidant that cells manufacture themselves. Depending on your profile, it may be present in your formula in two forms, both counted in the displayed dose. Added as a dedicated bioactive, it comes as free-form L-glycine: the amino acid on its own, not bound to another compound. The material selected is European Pharmacopoeia grade, with an assay between 98.5 and 101.5%. Delivered through magnesium, it comes as magnesium bisglycinate, a salt in which two glycine molecules are bound to a magnesium atom.

Glycine is an amino acid, a basic building block of proteins. In adults dissatisfied with their sleep, the trials find faster sleep onset and nights rated as better. In the laboratory, glycine lowers body temperature in animals, a signal that accompanies falling asleep. That result, measured in humans, is what grounds its place in the formula.

0 to 3 g

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Glycans

Hyaluronic Acid

Tissue structurePatented active

ExceptionHYAL® Star is a patented sodium hyaluronate from Roelmi HPC. It combines several molecular weights.

Hyaluronic acid is a long chain of sugars naturally present in the skin, where it contributes to water retention. In adults, pooled controlled trials measure more hydrated skin after supplementation. Best known from skin creams, it is taken here by mouth, the route those trials used. That result on hydration is what earns it a place in the formula.

0 to 200 mg

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Hyaluronic Acid
Glycans

Hyaluronic Acid

Tissue structurePatented active

ExceptionHYAL® Star is a patented sodium hyaluronate from Roelmi HPC. It combines several molecular weights.

Hyaluronic acid is a long chain of sugars naturally present in the skin, where it contributes to water retention. In adults, pooled controlled trials measure more hydrated skin after supplementation. Best known from skin creams, it is taken here by mouth, the route those trials used. That result on hydration is what earns it a place in the formula.

0 to 200 mg

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Minerals

Iodine

Cellular metabolism

Potassium iodide (KI) spray-dried onto a maltodextrin carrier, which accounts for most of its mass. Potassium iodide provides a fixed, known ratio between the salt and the iodine it contains, where seaweed extracts vary from batch to batch. This dilution carrier allows a microgram-scale dose to be distributed evenly throughout the formula. Iodine contributes to the normal production of thyroid hormones and normal thyroid function, and to normal cognitive function.

The body does not make iodine: the thyroid, a small gland in the neck, captures what food provides and concentrates it into its hormones. Iodine contributes to the normal production of thyroid hormones and normal thyroid function. Its useful window is narrow in both directions: too little and too much alike disturb the gland's work. That role is what earns iodine its place in the formula.

0 to 150 µg

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Iodine
Minerals

Iodine

Cellular metabolism

Potassium iodide (KI) spray-dried onto a maltodextrin carrier, which accounts for most of its mass. Potassium iodide provides a fixed, known ratio between the salt and the iodine it contains, where seaweed extracts vary from batch to batch. This dilution carrier allows a microgram-scale dose to be distributed evenly throughout the formula. Iodine contributes to the normal production of thyroid hormones and normal thyroid function, and to normal cognitive function.

The body does not make iodine: the thyroid, a small gland in the neck, captures what food provides and concentrates it into its hormones. Iodine contributes to the normal production of thyroid hormones and normal thyroid function. Its useful window is narrow in both directions: too little and too much alike disturb the gland's work. That role is what earns iodine its place in the formula.

0 to 150 µg

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Minerals

Iron

Mitochondrial energy

PHARMAGNESIA® FBg A is a fully reacted ferrous bisglycinate hydrochloride containing 17 to 22% elemental iron and no added excipient. Each iron atom (Fe2+) is bonded to two glycine molecules, which form the chelate's intrinsic ligand. Iron contributes to the reduction of tiredness and fatigue, and to normal oxygen transport in the body.

At the centre of haemoglobin, the protein of red blood cells, iron picks up oxygen in the lungs and releases it in the tissues. Iron contributes to normal formation of red blood cells and haemoglobin. In women before the menopause, pooled controlled trials measure higher haemoglobin levels and low iron stores less often. That result, measured in humans, is what earns iron its place in the formula.

0 to 21 mg

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Iron
Minerals

Iron

Mitochondrial energy

PHARMAGNESIA® FBg A is a fully reacted ferrous bisglycinate hydrochloride containing 17 to 22% elemental iron and no added excipient. Each iron atom (Fe2+) is bonded to two glycine molecules, which form the chelate's intrinsic ligand. Iron contributes to the reduction of tiredness and fatigue, and to normal oxygen transport in the body.

At the centre of haemoglobin, the protein of red blood cells, iron picks up oxygen in the lungs and releases it in the tissues. Iron contributes to normal formation of red blood cells and haemoglobin. In women before the menopause, pooled controlled trials measure higher haemoglobin levels and low iron stores less often. That result, measured in humans, is what earns iron its place in the formula.

0 to 21 mg

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Amino acids

L-Theanine

Systemic inflammation

Aqueous extract of green tea leaves (Camellia sinensis L.), standardised to a minimum of 40% L-theanine (HPLC). L-theanine is a non-proteinogenic amino acid, meaning it does not form part of the body's proteins. In nature, it is found almost exclusively in tea leaves. Extraction uses water alone, with no hexane, and concentrates 25 kg of leaves into 1 kg of extract. The theanine obtained is therefore the plant's own: no synthetic theanine is added. The remaining 60% is the natural green tea matrix, around 18% catechins (including 3 to 6% EGCG) and 0.3% caffeine. The leaves are harvested in China.

L-theanine is tea's characteristic amino acid, the one that gives the infusion its savoury taste, known as umami. In healthy adults, pooled controlled trials record a faster response on attention tasks, shortly after intake. After 50, a placebo-controlled trial finds the same gain from a single intake, and better accuracy in working memory (holding information in mind). These results are what earn it a place in the formula.

0 to 200 mg

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L-Theanine
Amino acids

L-Theanine

Systemic inflammation

Aqueous extract of green tea leaves (Camellia sinensis L.), standardised to a minimum of 40% L-theanine (HPLC). L-theanine is a non-proteinogenic amino acid, meaning it does not form part of the body's proteins. In nature, it is found almost exclusively in tea leaves. Extraction uses water alone, with no hexane, and concentrates 25 kg of leaves into 1 kg of extract. The theanine obtained is therefore the plant's own: no synthetic theanine is added. The remaining 60% is the natural green tea matrix, around 18% catechins (including 3 to 6% EGCG) and 0.3% caffeine. The leaves are harvested in China.

L-theanine is tea's characteristic amino acid, the one that gives the infusion its savoury taste, known as umami. In healthy adults, pooled controlled trials record a faster response on attention tasks, shortly after intake. After 50, a placebo-controlled trial finds the same gain from a single intake, and better accuracy in working memory (holding information in mind). These results are what earn it a place in the formula.

0 to 200 mg

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Phytonutrients

Lutein

Oxidative stressPatented active

XanMax® 2505 is a Tagetes erecta flower extract produced at a 400:1 extraction ratio and standardised to at least 25% lutein and 5% zeaxanthin. Lutein is a carotenoid of the xanthophyll family that naturally concentrates in the macula, the central area of the retina responsible for fine vision. The human body cannot synthesise it, so it must be obtained through the diet.

The eye stores lutein, a yellow pigment, around the point where sight is sharpest. That store can be measured in humans without a blood sample. Pooled trials pair lutein with zeaxanthin, a closely related pigment, and measure that store denser in adults whose eyes are healthy. In young healthy adults, a placebo-controlled trial also records a faster return of sight after glare. Its place in the formula rests on those human measurements.

0 to 20 mg

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Lutein
Phytonutrients

Lutein

Oxidative stressPatented active

XanMax® 2505 is a Tagetes erecta flower extract produced at a 400:1 extraction ratio and standardised to at least 25% lutein and 5% zeaxanthin. Lutein is a carotenoid of the xanthophyll family that naturally concentrates in the macula, the central area of the retina responsible for fine vision. The human body cannot synthesise it, so it must be obtained through the diet.

The eye stores lutein, a yellow pigment, around the point where sight is sharpest. That store can be measured in humans without a blood sample. Pooled trials pair lutein with zeaxanthin, a closely related pigment, and measure that store denser in adults whose eyes are healthy. In young healthy adults, a placebo-controlled trial also records a faster return of sight after glare. Its place in the formula rests on those human measurements.

0 to 20 mg

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Minerals

Magnesium

Genomic stability

Anhydrous magnesium bisglycinate, fully reacted: each magnesium atom is bonded to two glycine molecules, the smallest amino acid naturally present in the body. Unlike partially chelated bisglycinate on the market, this form contains no residual oxide or inorganic magnesium. The anhydrous form concentrates more elemental magnesium per gram. Result: a well-absorbed organic form, and a digestive tolerance that sets it apart from the laxative salts. Magnesium contributes to a reduction of tiredness and fatigue. Magnesium contributes to normal functioning of the nervous system. No excipient.

Magnesium is one of the minerals the body has to take from food. In laboratory studies, many enzymes depend on it inside every cell, including those that repair DNA. Magnesium contributes to normal psychological function and to the maintenance of normal bones. That constant role is what earns it a place in the formula.

0 to 360 mg

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Magnesium
Minerals

Magnesium

Genomic stability

Anhydrous magnesium bisglycinate, fully reacted: each magnesium atom is bonded to two glycine molecules, the smallest amino acid naturally present in the body. Unlike partially chelated bisglycinate on the market, this form contains no residual oxide or inorganic magnesium. The anhydrous form concentrates more elemental magnesium per gram. Result: a well-absorbed organic form, and a digestive tolerance that sets it apart from the laxative salts. Magnesium contributes to a reduction of tiredness and fatigue. Magnesium contributes to normal functioning of the nervous system. No excipient.

Magnesium is one of the minerals the body has to take from food. In laboratory studies, many enzymes depend on it inside every cell, including those that repair DNA. Magnesium contributes to normal psychological function and to the maintenance of normal bones. That constant role is what earns it a place in the formula.

0 to 360 mg

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Amino acids

N-Acetylcysteine

Oxidative stress

N-acetyl-L-cysteine of Ph. Eur. and USP grade, obtained by synthesis-fermentation from L-cysteine. The acetyl group stabilises the molecule: free L-cysteine oxidises spontaneously, whereas the acetylated form stays intact in solution. Once absorbed, it releases cysteine, the sulphur amino acid that laboratory work describes as rate-limiting in glutathione synthesis. White crystalline powder, freely soluble in water.

N-acetylcysteine is a derivative of cysteine, a sulphur-containing amino acid. In laboratory work, cysteine is the building block that runs short first in the making of glutathione, a molecule the body produces itself. Glycine, also present in the formula, supplies the second building block. In adults, pooled controlled trials measure a drop in blood markers of oxidative wear after oral supplementation. That result, measured in humans, is what earns it a place in the formula.

0 to 600 mg

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N-Acetylcysteine
Amino acids

N-Acetylcysteine

Oxidative stress

N-acetyl-L-cysteine of Ph. Eur. and USP grade, obtained by synthesis-fermentation from L-cysteine. The acetyl group stabilises the molecule: free L-cysteine oxidises spontaneously, whereas the acetylated form stays intact in solution. Once absorbed, it releases cysteine, the sulphur amino acid that laboratory work describes as rate-limiting in glutathione synthesis. White crystalline powder, freely soluble in water.

N-acetylcysteine is a derivative of cysteine, a sulphur-containing amino acid. In laboratory work, cysteine is the building block that runs short first in the making of glutathione, a molecule the body produces itself. Glycine, also present in the formula, supplies the second building block. In adults, pooled controlled trials measure a drop in blood markers of oxidative wear after oral supplementation. That result, measured in humans, is what earns it a place in the formula.

0 to 600 mg

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Lipids

Omega-3 (EPA+DHA)

Vascular tonePatented active

AvailOm® 50 High EPA is a lysine salt of omega-3 fatty acids, manufactured in France by Evonik Rexim. The free fatty acids are bonded to L-lysine obtained through fermentation. This ionic structure makes them water-soluble: their absorption no longer depends on bile secretion, which classic oils require. It also gives them an oxidation resistance that holds for several years without any additive, where liquid oils turn rancid. Dioxins, PCBs, heavy metals and aromatic hydrocarbons are controlled against European regulatory limits.

EPA and DHA are two omega-3 fatty acids that the formula supplies together. EPA and DHA contribute to the normal function of the heart (the beneficial effect is obtained with a daily intake of 250 mg of EPA and DHA). DHA contributes to maintenance of normal brain function (the beneficial effect is obtained with a daily intake of 250 mg of DHA). These contributions earn them their place in the formula.

0 to 2 g

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Omega-3 (EPA+DHA)
Lipids

Omega-3 (EPA+DHA)

Vascular tonePatented active

AvailOm® 50 High EPA is a lysine salt of omega-3 fatty acids, manufactured in France by Evonik Rexim. The free fatty acids are bonded to L-lysine obtained through fermentation. This ionic structure makes them water-soluble: their absorption no longer depends on bile secretion, which classic oils require. It also gives them an oxidation resistance that holds for several years without any additive, where liquid oils turn rancid. Dioxins, PCBs, heavy metals and aromatic hydrocarbons are controlled against European regulatory limits.

EPA and DHA are two omega-3 fatty acids that the formula supplies together. EPA and DHA contribute to the normal function of the heart (the beneficial effect is obtained with a daily intake of 250 mg of EPA and DHA). DHA contributes to maintenance of normal brain function (the beneficial effect is obtained with a daily intake of 250 mg of DHA). These contributions earn them their place in the formula.

0 to 2 g

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Metabolites

PQQ

Mitochondrial energyPatented active

MGCPQQ® is a pyrroloquinoline quinone disodium dihydrate of more than 99% purity, produced by fermenting a strain of Hyphomicrobium denitrificans. PQQ is a redox cofactor with a tricyclic aromatic structure, naturally present in trace amounts in foods such as kiwi, parsley, green tea and breast milk. This form provides the stability and solubility sought for oral use and is the form used in the majority of published clinical trials. Manufactured by Mitsubishi Gas Chemical.

PQQ is a quinone, a molecule that exchanges electrons. In chemistry, it runs through these exchanges without degrading. In adults, placebo-controlled trials measure gains in attention, memory or language depending on the trial, after oral supplementation. These gains, measured in humans, earn PQQ its place in the formula.

0 to 20 mg

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PQQ
Metabolites

PQQ

Mitochondrial energyPatented active

MGCPQQ® is a pyrroloquinoline quinone disodium dihydrate of more than 99% purity, produced by fermenting a strain of Hyphomicrobium denitrificans. PQQ is a redox cofactor with a tricyclic aromatic structure, naturally present in trace amounts in foods such as kiwi, parsley, green tea and breast milk. This form provides the stability and solubility sought for oral use and is the form used in the majority of published clinical trials. Manufactured by Mitsubishi Gas Chemical.

PQQ is a quinone, a molecule that exchanges electrons. In chemistry, it runs through these exchanges without degrading. In adults, placebo-controlled trials measure gains in attention, memory or language depending on the trial, after oral supplementation. These gains, measured in humans, earn PQQ its place in the formula.

0 to 20 mg

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Minerals

Selenium

Oxidative stress

L-selenomethionine, an organic form of selenium where the selenium atom replaces sulphur in methionine, an essential amino acid. This form exactly replicates the selenium naturally present in food (cereals, Brazil nuts, legumes). Unlike inorganic forms (selenite, selenate), selenomethionine is recognised by intestinal amino acid transporters, providing significantly higher oral bioavailability. Selenium contributes to the normal function of the immune system and to the protection of cells from oxidative stress.

Selenium contributes to the normal thyroid function. In laboratory work, this mineral sits at the heart of a small family of enzymes, the selenoproteins. In adults, controlled trials measure a rise in these selenoproteins in the blood after oral supplementation. That role is what earns it a place in the formula.

0 to 100 µg

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Selenium
Minerals

Selenium

Oxidative stress

L-selenomethionine, an organic form of selenium where the selenium atom replaces sulphur in methionine, an essential amino acid. This form exactly replicates the selenium naturally present in food (cereals, Brazil nuts, legumes). Unlike inorganic forms (selenite, selenate), selenomethionine is recognised by intestinal amino acid transporters, providing significantly higher oral bioavailability. Selenium contributes to the normal function of the immune system and to the protection of cells from oxidative stress.

Selenium contributes to the normal thyroid function. In laboratory work, this mineral sits at the heart of a small family of enzymes, the selenoproteins. In adults, controlled trials measure a rise in these selenoproteins in the blood after oral supplementation. That role is what earns it a place in the formula.

0 to 100 µg

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Phytonutrients

Sulforaphane

Autophagy & SenescencePatented active

Sulfodyne® is a broccoli seed extract (Brassica oleracea var. italica) patented by Ingood by Olga, standardized for free, stabilized sulforaphane. Most broccoli extracts supply glucoraphanin, an inactive precursor that gut flora must hydrolyse to release sulforaphane, a conversion that depends on the microbiome and on gastric acidity. A patented stabilization process delivers the isothiocyanate directly in its active form, with no intermediate enzymatic step. European seed origin, manufactured in France.

Sulforaphane is a sulphur molecule that cabbage and broccoli release when they are chewed. In adults exposed to air pollution, controlled trials measure a rise in the urinary elimination of unwanted compounds after oral supplementation. A placebo-controlled trial also records faster thinking and better short-term memory in healthy older adults. These results, measured in humans, are what earn sulforaphane its place in the formula.

0 to 20 mg

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Sulforaphane
Phytonutrients

Sulforaphane

Autophagy & SenescencePatented active

Sulfodyne® is a broccoli seed extract (Brassica oleracea var. italica) patented by Ingood by Olga, standardized for free, stabilized sulforaphane. Most broccoli extracts supply glucoraphanin, an inactive precursor that gut flora must hydrolyse to release sulforaphane, a conversion that depends on the microbiome and on gastric acidity. A patented stabilization process delivers the isothiocyanate directly in its active form, with no intermediate enzymatic step. European seed origin, manufactured in France.

Sulforaphane is a sulphur molecule that cabbage and broccoli release when they are chewed. In adults exposed to air pollution, controlled trials measure a rise in the urinary elimination of unwanted compounds after oral supplementation. A placebo-controlled trial also records faster thinking and better short-term memory in healthy older adults. These results, measured in humans, are what earn sulforaphane its place in the formula.

0 to 20 mg

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Amino acids

Taurine

Mitochondrial energy

Synthetic taurine, a non-proteinogenic sulphur amino acid. Unlike the 20 protein amino acids, taurine is not incorporated into proteins: it remains free in tissues. It naturally concentrates in the heart, brain, retina and skeletal muscles. The body synthesises it from cysteine, and its dietary sources are almost exclusively animal. Obtained by chemical synthesis, it is chemically identical to natural taurine.

Taurine is an amino acid found in abundance in the human body. Energy drinks have given it a stimulant reputation that belongs to their caffeine. In adults, pooled controlled trials measure lower blood pressure and less fat in the blood. The same trials report that the body responds better to sugar. These results, measured in humans, are what place it in the formula.

0 to 3 g

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Taurine
Amino acids

Taurine

Mitochondrial energy

Synthetic taurine, a non-proteinogenic sulphur amino acid. Unlike the 20 protein amino acids, taurine is not incorporated into proteins: it remains free in tissues. It naturally concentrates in the heart, brain, retina and skeletal muscles. The body synthesises it from cysteine, and its dietary sources are almost exclusively animal. Obtained by chemical synthesis, it is chemically identical to natural taurine.

Taurine is an amino acid found in abundance in the human body. Energy drinks have given it a stimulant reputation that belongs to their caffeine. In adults, pooled controlled trials measure lower blood pressure and less fat in the blood. The same trials report that the body responds better to sugar. These results, measured in humans, are what place it in the formula.

0 to 3 g

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Vitamins

Vitamin B12

Genomic stability

Vitamin B12 as methylcobalamin, one of the two coenzyme forms found in human physiology. Cyanocobalamin, the most widespread synthetic form on the market, occurs in human tissues only in trace amounts. Methylcobalamin takes part in the methionine cycle and homocysteine metabolism. Vitamin B12 contributes to normal energy-yielding metabolism, normal red blood cell formation and normal functioning of the nervous system.

A cobalt atom sits at the centre of the vitamin B12 molecule, which the human body cannot make. Vitamin B12 contributes to normal psychological function and to the reduction of tiredness and fatigue. Its absorption depends on a protein from the stomach, whose production falls with the years. That nutritional role is what earns it a place in the formula.

0 to 1,000 µg

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Vitamin B12
Vitamins

Vitamin B12

Genomic stability

Vitamin B12 as methylcobalamin, one of the two coenzyme forms found in human physiology. Cyanocobalamin, the most widespread synthetic form on the market, occurs in human tissues only in trace amounts. Methylcobalamin takes part in the methionine cycle and homocysteine metabolism. Vitamin B12 contributes to normal energy-yielding metabolism, normal red blood cell formation and normal functioning of the nervous system.

A cobalt atom sits at the centre of the vitamin B12 molecule, which the human body cannot make. Vitamin B12 contributes to normal psychological function and to the reduction of tiredness and fatigue. Its absorption depends on a protein from the stomach, whose production falls with the years. That nutritional role is what earns it a place in the formula.

0 to 1,000 µg

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Vitamins

Vitamin B6 (P5P)

Genomic stability

Active form of vitamin B6: pyridoxal-5-phosphate (P5P) monohydrate, diluted on maltodextrin, its only declared carrier. P5P is the vitamer enzymes bind to: it serves as a coenzyme for more than 100 enzymes, particularly in amino acid metabolism and neurotransmitter synthesis. Its activation route proceeds through phosphorylation by pyridoxal kinase, without the additional oxidation step that pyridoxine requires. Vitamin B6 contributes to normal functioning of the nervous system and to the reduction of tiredness and fatigue.

The body relies on food each day for its vitamin B6. Vitamin B6 contributes to normal protein and glycogen metabolism. In laboratory work, it assists the enzyme that mobilises glycogen, our stored sugar. It is also needed to build part of the body's own vitamin B3 from tryptophan, an amino acid in proteins. That everyday role is what earns it a place in the formula.

0 to 7 mg

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Vitamin B6 (P5P)
Vitamins

Vitamin B6 (P5P)

Genomic stability

Active form of vitamin B6: pyridoxal-5-phosphate (P5P) monohydrate, diluted on maltodextrin, its only declared carrier. P5P is the vitamer enzymes bind to: it serves as a coenzyme for more than 100 enzymes, particularly in amino acid metabolism and neurotransmitter synthesis. Its activation route proceeds through phosphorylation by pyridoxal kinase, without the additional oxidation step that pyridoxine requires. Vitamin B6 contributes to normal functioning of the nervous system and to the reduction of tiredness and fatigue.

The body relies on food each day for its vitamin B6. Vitamin B6 contributes to normal protein and glycogen metabolism. In laboratory work, it assists the enzyme that mobilises glycogen, our stored sugar. It is also needed to build part of the body's own vitamin B3 from tryptophan, an amino acid in proteins. That everyday role is what earns it a place in the formula.

0 to 7 mg

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Vitamins

Vitamin B9

Genomic stabilityPatented active

Vitamin B9 as calcium L-5-methyltetrahydrofolate (5-MTHF), stabilised crystalline form. 5-MTHF is the biologically active form of folate, directly usable by the body. Unlike synthetic folic acid, it requires no enzymatic reduction by MTHFR (methylenetetrahydrofolate reductase), an enzyme whose activity is reduced in a significant portion of the population due to common genetic polymorphisms. Folate contributes to maternal tissue growth during pregnancy and to the normal function of the immune system.

Vitamin B9, also known as folate, is one of the vitamins the body cannot make for itself. Folate contributes to normal blood formation. In laboratory work, the bone marrow, which produces blood cells, draws on it continuously to build each new cell. Men and women need it throughout adult life, well beyond pregnancy. That service to the blood is what earns it a place in the formula.

0 to 500 µg

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Vitamin B9
Vitamins

Vitamin B9

Genomic stabilityPatented active

Vitamin B9 as calcium L-5-methyltetrahydrofolate (5-MTHF), stabilised crystalline form. 5-MTHF is the biologically active form of folate, directly usable by the body. Unlike synthetic folic acid, it requires no enzymatic reduction by MTHFR (methylenetetrahydrofolate reductase), an enzyme whose activity is reduced in a significant portion of the population due to common genetic polymorphisms. Folate contributes to maternal tissue growth during pregnancy and to the normal function of the immune system.

Vitamin B9, also known as folate, is one of the vitamins the body cannot make for itself. Folate contributes to normal blood formation. In laboratory work, the bone marrow, which produces blood cells, draws on it continuously to build each new cell. Men and women need it throughout adult life, well beyond pregnancy. That service to the blood is what earns it a place in the formula.

0 to 500 µg

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Vitamins

Vitamin C

Oxidative stress

L-ascorbic acid coated with ethylcellulose, an inert food-grade polymer. This coating protects vitamin C from oxidation and moisture degradation, two major weaknesses of unprotected ascorbic acid. Applied by aqueous granulation, it is the only inactive component of the selected material. The human body does not synthesise vitamin C (unlike most mammals). It contributes to the normal function of the immune system and to the protection of cells from oxidative stress.

Vitamin C is a water-soluble nutrient, indispensable to the work of many enzymes. It contributes to the reduction of tiredness and fatigue, and to normal energy-yielding metabolism. In laboratory work, it helps cells make carnitine, a carrier of fats. Those functions are what earn it a place in the formula.

0 to 750 mg

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Vitamin C
Vitamins

Vitamin C

Oxidative stress

L-ascorbic acid coated with ethylcellulose, an inert food-grade polymer. This coating protects vitamin C from oxidation and moisture degradation, two major weaknesses of unprotected ascorbic acid. Applied by aqueous granulation, it is the only inactive component of the selected material. The human body does not synthesise vitamin C (unlike most mammals). It contributes to the normal function of the immune system and to the protection of cells from oxidative stress.

Vitamin C is a water-soluble nutrient, indispensable to the work of many enzymes. It contributes to the reduction of tiredness and fatigue, and to normal energy-yielding metabolism. In laboratory work, it helps cells make carnitine, a carrier of fats. Those functions are what earn it a place in the formula.

0 to 750 mg

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Vitamins

Vitamin D3

Genomic stability

L-VITAL® D3 PW25 Fiber is a liposomal cholecalciferol powder deposited on an insoluble plant-fibre matrix. The finished ingredient is manufactured in France, and its matrix combines pea fibre, sunflower lecithin, inulin and coconut MCT oil. Vitamin D contributes to the maintenance of normal bones, to the normal function of the immune system and to normal absorption/utilisation of calcium and phosphorus.

Cholecalciferol, or vitamin D3, is a fat-soluble vitamin that the body holds in reserve. At our latitudes, the winter sun sits too low for the skin to produce it. Vitamin D contributes to the maintenance of normal muscle function and has a role in the process of cell division. In laboratory work, it behaves like a hormone that the liver and the kidneys activate in turn. Those recognised functions are what earn it a place in the formula.

0 to 70 µg

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Vitamin D3
Vitamins

Vitamin D3

Genomic stability

L-VITAL® D3 PW25 Fiber is a liposomal cholecalciferol powder deposited on an insoluble plant-fibre matrix. The finished ingredient is manufactured in France, and its matrix combines pea fibre, sunflower lecithin, inulin and coconut MCT oil. Vitamin D contributes to the maintenance of normal bones, to the normal function of the immune system and to normal absorption/utilisation of calcium and phosphorus.

Cholecalciferol, or vitamin D3, is a fat-soluble vitamin that the body holds in reserve. At our latitudes, the winter sun sits too low for the skin to produce it. Vitamin D contributes to the maintenance of normal muscle function and has a role in the process of cell division. In laboratory work, it behaves like a hormone that the liver and the kidneys activate in turn. Those recognised functions are what earn it a place in the formula.

0 to 70 µg

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Vitamins

Vitamin K2-MK7

Tissue structurePatented active

Pharmaquinone® is a synthetic vitamin K2 as all-trans MK-7, containing more than 1% vitamin K2 and carried on microcrystalline cellulose using MCT oil. This configuration is the biologically active form of MK-7. Its extended half-life, approximately 72 hours compared with a few hours for MK-4, supports stable blood levels with a single daily intake. Vitamin K contributes to the maintenance of normal bones. Vitamin K contributes to normal blood clotting.

Vitamin K2-MK7 is a form of vitamin K, a nutrient the diet has to supply. In the laboratory, it activates a bone protein that holds calcium. Vitamin K contributes to the maintenance of normal bones. Another bioactive in the formula, vitamin D3 helps the body absorb that calcium. That role in bone is what earns it a place in the formula.

0 to 180 µg

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Vitamin K2-MK7
Vitamins

Vitamin K2-MK7

Tissue structurePatented active

Pharmaquinone® is a synthetic vitamin K2 as all-trans MK-7, containing more than 1% vitamin K2 and carried on microcrystalline cellulose using MCT oil. This configuration is the biologically active form of MK-7. Its extended half-life, approximately 72 hours compared with a few hours for MK-4, supports stable blood levels with a single daily intake. Vitamin K contributes to the maintenance of normal bones. Vitamin K contributes to normal blood clotting.

Vitamin K2-MK7 is a form of vitamin K, a nutrient the diet has to supply. In the laboratory, it activates a bone protein that holds calcium. Vitamin K contributes to the maintenance of normal bones. Another bioactive in the formula, vitamin D3 helps the body absorb that calcium. That role in bone is what earns it a place in the formula.

0 to 180 µg

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Phytonutrients

Zeaxanthin

Oxidative stressPatented active

XanMax® 2505 is the carrier raw material, an extract of Tagetes erecta flowers obtained with hexane and ethanol at a 400:1 extraction ratio. Its xanthophyll crystals are formulated with dextrin, gum acacia and tocopherols, which slow oxidation of the pigment. A single weighing supplies both lutein and zeaxanthin, in the ratio set by the standardisation of the material: at least 25% lutein and 5% zeaxanthin.

Zeaxanthin is a yellow pigment that the eye holds in reserve. Its close cousin, lutein, is also present in the formula, and it is that association the studies have covered. In adults with healthy eyes, pooled trials measure a denser deposit of pigment after oral supplementation. A trial against placebo, in young healthy adults, measures a faster return of sight after glare. These measurements, made in humans, are the reason it is in the formula.

0 to 4 mg

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Zeaxanthin
Phytonutrients

Zeaxanthin

Oxidative stressPatented active

XanMax® 2505 is the carrier raw material, an extract of Tagetes erecta flowers obtained with hexane and ethanol at a 400:1 extraction ratio. Its xanthophyll crystals are formulated with dextrin, gum acacia and tocopherols, which slow oxidation of the pigment. A single weighing supplies both lutein and zeaxanthin, in the ratio set by the standardisation of the material: at least 25% lutein and 5% zeaxanthin.

Zeaxanthin is a yellow pigment that the eye holds in reserve. Its close cousin, lutein, is also present in the formula, and it is that association the studies have covered. In adults with healthy eyes, pooled trials measure a denser deposit of pigment after oral supplementation. A trial against placebo, in young healthy adults, measures a faster return of sight after glare. These measurements, made in humans, are the reason it is in the formula.

0 to 4 mg

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Minerals

Zinc

Genomic stability

PHARMAGNESIA® ZBg A is a zinc bisglycinate containing 26.8 to 34.5% zinc and no added excipient. In this complex, each zinc atom is bonded to two glycine molecules, the smallest amino acid naturally present in the body. Zinc contributes to the normal function of the immune system and to the protection of cells from oxidative stress.

Zinc is a mineral the body cannot make: it comes entirely from food. In laboratory work, many enzymes carry zinc within their structure and do not work without it. Zinc contributes to normal metabolism of vitamin A and to normal protein synthesis, the making of the body's proteins. That role in the work of cells is what earns it a place in the formula.

0 to 15 mg

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Zinc
Minerals

Zinc

Genomic stability

PHARMAGNESIA® ZBg A is a zinc bisglycinate containing 26.8 to 34.5% zinc and no added excipient. In this complex, each zinc atom is bonded to two glycine molecules, the smallest amino acid naturally present in the body. Zinc contributes to the normal function of the immune system and to the protection of cells from oxidative stress.

Zinc is a mineral the body cannot make: it comes entirely from food. In laboratory work, many enzymes carry zinc within their structure and do not work without it. Zinc contributes to normal metabolism of vitamin A and to normal protein synthesis, the making of the body's proteins. That role in the work of cells is what earns it a place in the formula.

0 to 15 mg

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Quality and traceability

Four commitments frame the material you receive, from its approval to its packaging.

Quality tests

Risk-based analytical controls and documents

View the reference composition sheet

Approved materials

Ten questions reviewed before any order

FR manufacturing

In-house lab in France

Eco-responsible

Reduced plastic

Methodology

Our bioactive selection is based on the most robust longevity studies, reviewed by a multidisciplinary body of independent experts (doctors, pharmacists, nutritionists). Out of 127 bioactives evaluated since inception, 96 have been rejected. This rigor explains why every ingredient in your formula must justify its place, sources in hand.

01

Systematic review

Each bioactive is selected after analysis of meta-analyses and randomized scientific trials available on PubMed and Cochrane.

02

Bioavailable forms

We prioritize the most absorbable forms (citrate over oxide), whose exposure in humans is documented, and we set aside those that carry a safety signal.

03

Evidence-based dosages

Dosages are based on scientific studies that have demonstrated efficacy, not minimum recommended daily intakes.

04

Verified interactions

Each combination is verified for synergies (e.g., D3+K2) and potential interactions to avoid.

The price of precision

The standard industry optimizes cost per capsule. Singular optimizes biological benefit per milligram absorbed. For instance:

BioactiveGeneric formSingular formCost diffBenefit
MagnesiumOxide
Bisglycinate
8-12×Absorbed, no laxative effect
Vitamin B12Cyanocobalamin
Methylcobalamin
5×Non-cyano coenzyme form
FolateFolic acid
Calcium L-5-MTHFPatented active
10-15×Active form, no reduction step
CurcuminStandard extract
Meriva™ (phospholipid complex)Patented active
6-8×Absorbed without piperine
PQQGeneric disodium salt
MGCPQQ® (fermentation)Patented active
4-6×Clinically studied form
Omega-3Fish oil (triglyceride or ethyl ester)
AvailOm® (lysine salt)Patented active
3-5×Stable; absorbed 1.6× vs triglyceride, 9.3× vs ethyl ester

This systemic surcharge does not appear on your invoice. It is built into our quality commitment.

Discover your personalized formula

Each bioactive is dosed to the milligram according to the applicable formulation rules. Your first formulation is free.