The Foundations
The convictions, expertise and standards behind every Singular formula.
Kilian Füg
Engineering in service of the living
Singular was born from an observation of obsolescence.
Seeking to optimize my loved ones' longevity, I discovered an industry stuck in the last century. Everything is smoke and mirrors: dosages hidden behind "proprietary blends" and marketing promises disconnected from the latest science.
I spent fifteen years building high-precision systems where complexity reigns. In 2010, I founded Sogexia and launched the first online payment accounts. Rather than assembling existing building blocks, I coded an entire banking architecture from a blank page. This technological depth notably convinced the BNP Paribas group to become a shareholder.
With this expertise, I decided to apply the same rigor from financial flows to biological flows. Applying an analytical framework, the verdict is clear: preventive health is treated with staggering technical aberration. Identical pills for everyone while our biologies are unique. Fixed dosages while our needs evolve. An industry built on a statistical average that doesn't exist.
I understood that to achieve the standard of excellence I was seeking, I would have to build it entirely. Not just a brand. A complete system where the formula is dictated by our own biology, and not by a marketing spreadsheet.
To transform this vision into a system, I built a management team and a scientific committee capable of carrying it forward every day with the rigor it deserves.
One conviction, multiple expertises
Singular is not a one man's intuition. It is the synthesis of a college of independent experts (doctors, pharmacists, nutritionists) whose work shapes our product and its evolution according to the latest science. We don't publish their names: they practice, they research, they don't sell. But their rigor structures every formula you receive.
Total verticality
The laboratory
We don't outsource: we control. Every formula is assembled in France, in our own laboratory, to ensure an unbroken chain of trust and a complete traceability.
- 100% in-house French manufacturing
- ISO 22000 standard
- Batch-by-batch traceability
- Continuous quality control
The technology
At the heart of Singular, a probabilistic engine that rejects averages. It doesn't seek to simplify your biology, but to decode it at the N=1 scale.
- Integration of 28 biomarkers
- Over one billion combinations explored
- Milligram-precise dosing
- Continuous formulation rules updates
- Health data hosted with HDS-certified providers
The selection
Every bioactive in our library fights for its survival: it must pass three barriers before entering our engine. This rigor explains why some popular ingredients never appear in our formulas.
Proof of efficacy
Meta-analyses or randomized controlled trials published in peer-reviewed journals. Observational studies alone are insufficient.
Superior bioavailability
The chemical form must demonstrate significantly better absorption than the generic form. The surcharge is absorbed by Singular.
No redundancy
The ingredient must provide a biological function not covered by other components. No marketing stacking.
Our library is not a catalog of trendy ingredients. It is a curated selection where every molecule has proven its worth.
The 12 hallmarks of aging
Our approach targets the 12 fundamental mechanisms of cellular aging identified by López-Otín et al. (2023). Each bioactive in your formula is selected based on its relevance to one or more of these hallmarks.
Genomic instability
Accumulation of DNA damage over time, affecting genome integrity and cellular function.
Targeted bioactives
Genomic instability
Accumulation of DNA damage over time, affecting genome integrity and cellular function.
Targeted bioactives
Telomere attrition
Progressive shortening of telomeres with each cell division, limiting renewal capacity.
Targeted bioactives
Telomere attrition
Progressive shortening of telomeres with each cell division, limiting renewal capacity.
Targeted bioactives
Epigenetic alterations
Changes in DNA methylation and histone patterns affecting gene expression.
Targeted bioactives
Epigenetic alterations
Changes in DNA methylation and histone patterns affecting gene expression.
Targeted bioactives
Loss of proteostasis
Dysfunction of protein quality control mechanisms, leading to accumulation of misfolded proteins.
Targeted bioactives
Loss of proteostasis
Dysfunction of protein quality control mechanisms, leading to accumulation of misfolded proteins.
Targeted bioactives
Disabled macroautophagy
Decline of the cellular recycling system that eliminates damaged components and protein aggregates.
Targeted bioactives
Disabled macroautophagy
Decline of the cellular recycling system that eliminates damaged components and protein aggregates.
Targeted bioactives
Deregulated nutrient sensing
Alteration of nutrient-sensing signaling pathways (mTOR, AMPK, sirtuins).
Targeted bioactives
Deregulated nutrient sensing
Alteration of nutrient-sensing signaling pathways (mTOR, AMPK, sirtuins).
Targeted bioactives
Mitochondrial dysfunction
Decline in cellular energy production and increase in reactive oxygen species.
Targeted bioactives
Mitochondrial dysfunction
Decline in cellular energy production and increase in reactive oxygen species.
Targeted bioactives
Cellular senescence
Accumulation of growth-arrested cells that secrete inflammatory factors (SASP).
Targeted bioactives
Cellular senescence
Accumulation of growth-arrested cells that secrete inflammatory factors (SASP).
Targeted bioactives
Stem cell exhaustion
Decline in number and function of stem cells, reducing tissue regenerative capacity.
Targeted bioactives
Stem cell exhaustion
Decline in number and function of stem cells, reducing tissue regenerative capacity.
Targeted bioactives
Altered intercellular communication
Dysfunction of signals between cells, affecting tissue and organ coordination.
Targeted bioactives
Altered intercellular communication
Dysfunction of signals between cells, affecting tissue and organ coordination.
Targeted bioactives
Chronic inflammation
Persistent low-grade inflammation (inflammaging) contributing to many age-related pathologies.
Targeted bioactives
Chronic inflammation
Persistent low-grade inflammation (inflammaging) contributing to many age-related pathologies.
Targeted bioactives
Dysbiosis
Gut microbiome imbalance affecting immunity, metabolism, and intestinal barrier.
Targeted bioactives
Dysbiosis
Gut microbiome imbalance affecting immunity, metabolism, and intestinal barrier.
Targeted bioactives
Studies and research
All our bioactives are documented by scientific studies. Consult PubMed references for each component of your formula.
Strategic watch and pipeline
Longevity science evolves rapidly. We continuously monitor the Rejuvenation Roadmap (LifeSpan.io) to distinguish future interventions (gene therapies, senolytics, etc.) from scientifically validated molecules.
Singular acts as a safety filter: we only integrate actives that have reached the stage of solid human evidence.
VIEW THE ROADMAPWhat we refuse
No miracle powders. No hidden dosages. No "works for everyone."
No beliefs
Every ingredient is selected based on published scientific data. No trends. No fads. Science, or nothing.
No opacity
The origin, dosage, and justification for each bioactive are accessible in your space. What you take, you know why you take it.
No averages
Your formula is calculated for your biology. Not for a healthy 40-year-old man. For you.
No compromise
We refuse the generic forms that the industry imposes for cost savings. Every bioactive is selected in its most bioavailable form, even when it costs ten times more.
Discover what your biology reveals
Your first formulation is free.